Earlier this week, a serious vulnerability in the OpenSSL encryption library was discovered and made public. This vulnerability has made a vast number of web sites using HTTPS to be insecure, potentially exposing sensitive user data including passwords, email addresses, login names etc. (details about the bug can be found at http://heartbleed.com). Our team immediately worked to ensure our web sites and our users’ data were secure. Upon investigation, we discovered that none of the Schwartz Lab web sites are vulnerable to this bug. Our servers were not running the version of OpenSSL which contained the heartbleed vulnerability and thus none of our users’ data has been compromised or put at risk. Despite this, we encourage registered users of plogo.uconn.edu to change their account passwords if they have used the same password on any other web site(s) because your password may have been compromised via those site(s).
-The pLogo Development Team
We just released a new version of pLogo (v1.2.0).
New functionalities:
1. The ability to retain duplicate n-mers in the foreground and background (via checkboxes). Note, it is best to remove duplicates, unless you are confident that the contents of your foreground and/or background data sets are quantitative.
2. The ability to number pLogo columns according to proteolytic cleavage numbering conventions (i.e., P3 P2 P1 P1′ P2′ P3′). This feature can be accessed in the pLogo customization tab to the left of the pLogo image by selecting “proteolytic” for column numbering.
Other changes:
3. Some of you might have noticed the long initial page load, this issue has been fixed.
4. Fixed a bug causing pLogo generation to fail for a handful of kinases.
5. Fixed a display issue where residue positions in the “initial fixed positions” table were off by 1.
6. Fixed a bug causing pLogo images to be saved with the incorrect file extension in certain cases.
7. Fixed a bug where redrawing pLogos via the “customize” menu would set the y-axis maximum value to a fixed value (rather than an image normalized value).
8. Fixed a bug where editing a public job would change the job/image for everyone (including the initial owner of the job).
9. Improved error reporting/handling in a few specific cases.
Feel free to contact us if you would like to see a new pLogo feature added (the new features were added by user request). And please let us know if you find any bugs…
Happy New Year!
-The pLogo Development Team
The pLogo web site went down yesterday (11.19.13) due to a large power outage at the University of Connecticut. To those of you who tried to use the site yesterday, we apologize. The site is live again and user data has not been affected by the outage.
-The pLogo Development Team
We just updated the current pLogo web site to version 1.1.0.
Here are the release notes:
-pLogo generation has been optimized for all organism background data sets provided on the web site. Average pLogo image generation time has gone from 5-7 seconds down to 2-3 seconds.
-New feature added: foreground sequences may now optionally be subtracted from the background by checking the box labeled “subtract foreground sequences from background” in the background selection box. Please note using this option may increase pLogo generation times substantially.
-The export menu has been improved to be more robust and easier to use. This should reduce the likelihood of encountering errors while exporting.
-We fixed a bug causing pLogos which were exported in EPS/PDF format to not display properly in the user job history.
-pLogo tutorial videos are now available under the “help” tab (click “help”, then click “videos”). Additional videos coming soon!
As always please feel free to send us your feedback.
-The pLogo Development Team
Welcome to our new pLogo generation web site. This page will be used in the future to announce version updates and other useful news about the web tool. Our goal is to create a user-friendly, interactive, and functional environment to explore biological sequence motifs. Feel free to contact us with any questions and/or suggestions using the “contact” tab above. Enjoy!
-The pLogo Development Team
The software provided on this website may be used freely by users from academic
and non-profit
organizations. Users from the commercial sector should
contact us.